Solution of di-chloramine-t



FERDINAND H. YOUNG, OF CHICAGO, ILLINOIS, ASSIGNOR TO THE ABBOTT LABORA- TORIES, OF CHICAGO, ILLINOIS, A CORPORATION OI ILLINOIS.

SOLUTION OF lDI-CHLORAIVIINlE-T.

No Drawing.

T all whom it mag concave:

Be it known that I, FERDINAND II. YOUNG, a citizen of the United States, residing at Chicago, in the county of Cook and State of Illinois, have invented certain new and useful Improvements in Solutions of Di-ChloramineT, of which the following is a specification.

Di-chlorainine-T is a germicide or antiseptic used for many purposes and particularly for spraying on wounds. This material, which heretofore has been furnished in powdered crystalline form, or in the form of tablets, is oil-soluble, and is dissolved in a relatively inexpensive solvent, such-as chlorcosane, theoretically, just before it is to be used, the reason of course being that when while,

dichloramine-T is made up into such a solution, it will rapidly degenerate or deteriorate, lose strength, and become unfit for use.

Unfortunately, however, the. Di-chloramine- 'I does not dissolve quickly, and the time taken to dissolve same may, in some cases, mean the difference betweenlife and death;

solution may be ruined by the hightemperatureemployed. Owing to the above difiiculties, there is often a strong temptation on the part of the physician to make up a comparatively large batch of such solution in the hope that it will all be used before any substantial deterioration occurs, with the inevitable result that sooner or later some of the left over stale solution is used, the desired effect is not secured, the patient suffers and the manufacturer unjustly receives blafne for furnishing an inferior article.

In applying my invention to the specific case cited, I made numerous tests and experiments in the effort to discover some way of producing a strong liquor or preliminary solution of dichloramine-I, the solventor' vehicle of which would have no edectupon on the other hand, if an attempt bemade to hasten the process by heating, the ten the process by heat, nor will he Application filed December 31, 1919. Serial No. 348,666.

the dichloramine-T when in solution and which would not affect the eiiicacy of the germicide when diluted with chlorcosane. Monochlorbenzene and o-dichlorbenzene, I have discovered can successfully be employed in which to dissolve the solid powder or crystals of dichlor'amine-I. Such a solution of dichloramine-T in either of the said liquids, is permanent for all practical purposes, when kept under ordinary conditions; and, furthermore, neither of the liquids has any undesirable effect upon the ultimate solution as used. Obviously, the advantages of being able to take a few drops of the strong dichloramine-T liquor and dilute it with the required amount of chlorcosane, over the laborious dissolving of the solid in the chlorcosane, are numerous, it being merely necessary to stir up the solution for a second or two, whereupon the germicide is ready for use.

The making up-of such a germicide solution according to my invention is so rapid, easy, and convenient, that the'user is not subjected to the temptation of trying to hasbe likely to use a left-over: or stale solution.

1. The improvement in the art of preparing a solution of dichloramine-T, which consists in first dissolving the solid material in a chlorinated benzene with which it will not deteriorate, and subsequently incorporating a portion oft-he concentrated liquor solving the dichloramine-T in monochlorbenzene, and subsequently, when required for use, diluting a portion of the concentrated liquor with the required amount of chlorcosane. Y FERDINAND I'I. YOUNG. 

